Anxanil; Atarax; Hydroxyzine dihydrochloride; Rezine; Vistaril;
Hydroxyzine is a first-generation antihistamine, of the piperazine class that is an H1 receptor antagonist. It is used primarily as an antihistamine for the treatment of itches and irritations, an antiemetic for the reduction of nausea, as a weak analgesic by itself and as an opioid potentiator, and as an anxiolytic for the treatment of anxiety. The drug is available in two formulations, the pamoate and the dihydrochloride or hydrochloride salts. Vistaril®, Equipose®, Masmoran®, Paxistil®, and Vistaril Pamoate® are preparations of the pamoate salt whilst Atarax®, Alamon®, Aterax®, Durrax®, Tran-Q®, Orgatrax®, Quiess®, Vistaril Parenteral®, and Tranquizine® are hydroxyzine hydrochloride.